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IN VITRO ANTI-TRYPANOSOMAL ACTIVITY OF ANACARDIUM OCCIDENTALE AND CYMBOPOGON CITRATES AGAINST TRYPANOSOMA BRUCEI IN MICE
Olorunsogbon, B. F. and Osho, I. B

ABSTRACT
The anti-trypanosomal effect of ethanolic extracts of Anacardium occidentale and Cymbopogon citrates was examined in vitro for their trypanocidal activity using Trypanosoma brucei as the test trypanosome at effective concentrations of 2mg, 10mg, and 20mg/ml. Complete elimination of motility or reduction of motility of the parasites when compared to control was observed as indices of trypanocidal effects. Extract of Anacardium occidentale was slightly more active than that of Cymbopogon citrates. The result suggested that these two plant extracts possessed some trypanocidal activities, which may require further investigation. The presence of phytochemical constituents such as Alkaloid, Glycosides, Saponins, tannin, and steroids could account for the observed activities and potency of some of the active extracts against trypanosomes


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The Beam journal of arts and science
ISSN: 1118-5953 www.uaspolysok.edu.ng/jounal